Nifedipine overdose

"nifedipine in the treatment of liver toxicity induced by acetaminophen overdose in mice "

acetaminophen is an analgesic and antipyretic drug, which is widely used by public and poisoning with this drug, is common. one of the most important adverse effects of acetaminophen poisoning is centrilobullar necrosis in hepatic cells, which depends on activity of microsomal cytochrome p-450 (cyp) enzymes. the aim of this investigation was to find out the protective effect of nifedipine again...

Nifedipine–pyrazine (2/1)

In the title compound, 2C(17)H(18)N(2)O(6)·C(4)H(4)N(2) [systematic name: 3,5-dimethyl 2,6-dimethyl-4-(2-nitro-phen-yl)-1,4-di-hydro-pyridine-3,5-dicarboxyl-ate-pyrazine (2/1)], the complete pyrazine molecule is generated by crystallographic inversion symmetry. The center of the pyrazine ring lies on an inversion center. The nifedipine mol-ecules are linked into chains along the c axis through ...

Hyperglycaemic effect of nifedipine.

histotoxic symptoms may be due to these, but the exact mechanism of action of thiocyanates is not known.4 Thiocyanate intoxication with blood concentrations above 200 mg/l may be rapidly corrected by haemodialysis, which reportedly removes several grams of the drug.5 We tried peritoneal dialysis but in the absence of clearance studies, which we could not do, we cannot comment on the procedure f...

Nifedipine GITS Package Insert

Barbicidal overdose

Acute severe methemoglobinaemia is an uncommon but life-threatening condition caused by a variety of oxidizing agents commonly used in both health care and industrial settings. Thus, recognition is important as it is readily treatable. The oxygen transport is compromised as a result of abnormal levels of oxidized haemoglobin, and this leads to skin discolouration and a variety of symptoms. Diag...